Endocrine Abstracts

Objective: The study aims to investigate the association between asymptomatic pyuria/bacteriuria at the initiation of SGLT2 inhibitors (SGLT2i) and urinary tract infection (UTI) risk in a cohort of women with type 2 diabetes mellitus (T2DM) (NCT05520684).Methods: The female outpatients with T2DM under follow-up in the department of internal medicine and initiated SGLT2i (dapagliflozin/empagliflozin) were included between February and September 2022. Excl...

Introduction: The main goal of treatment in Cushing’s disease (CD) is to induce remission as well as to restore reproductive function. We aimed to evaluate the reproductive status of the female patients with CD encountered in sexually active patients after surgical with/without medical treatments.Method: The retrospective data was obtained from the medical records of the 72 female patients diagnosed with CD at hospital registration system. The patie...

Subacute Thyroiditis (SAT) is a painful, self-limited inflammation of the thyroid gland. Guidelines recommend Non-Steroid Antiinflammatory Drugs (NSAIDs) for mild cases and steroids for moderate to severe cases. Early relapses can be seen in about 9-35%. The aim of this study was to investigate the clinical, laboratory, and imaging findings that may affect treatment selection and predict relapse.Materials and Methods: Forty SAT patients who applied to th...

Introduction: Adrenal gland involvement can be seen in about 25% of lymphomas. However, primary adrenal lymphomas (PAL) are rare. The most common is diffuse large B-cell lymphoma (DLBCL). It is seen usually after the age of 60 years as bilateral, large masses.Case report: A 64-year-old woman with a complaint of abdominal pain was referred to our clinic after bilateral surrenal masses were detected upon abdominal ultrasonography (USG) and computed tomogra...

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs.Dokuz Eylul University Adrenal Tumours Study Group database includes 596 patients by January 2016. Briefly, there are 332...

Introduction: Autoimmune polyglandular syndrome type 2 (APS2) is the most common form of the polyglandular failure syndromes. Seventy-five percent of cases occur in women. Adrenal insufficiency is the principal manifestation occurs with autoimmune thyroid disease or type I diabetes mellitus. The incidence of autoimmune thyroid diseases in APS2 is 70%; 30% Hashimoto’s thyroiditis, 20% non toxic goiter, 20% hypertyroidism is seen. We will discuss about a patient with APS2, ...

Aim: To compare macular pigment optical density (MPOD) in diabetic and non-diabetic patients by using heterochromatic flicker photometry and to investigate the correlation of MPOD with glycosylated hemoglobin (HbA1C), serum lipid levels and vitamin D levels.Methods: Sixty-seven patients with 10/0 visual acuity were divided into group 1 (controls, n: 35) and group 2 (diabetics without retinopathy, n: 32). MPOD was measured with a heteroc...

Introduction: Pentraxin 3 (PTX3) is an acute-phase protein that shares structural homology with C-reactive protein (CRP). PTX3 is produced in macrophages, endothelial cells, and adipocytes in response to inflammatory stimuli, whereas hepatocytes are the main source of CRP. Because obesity and metabolic syndrome (MetS) are considered chronic inflammatory states, PTX3 might be involved in the pathogenesis of obesity and MetS as well as CRP. In this study, we aimed to investigate...

Introduction: Giant cell granulomatous hypophysitis is a rare chronic inflammatory disorder of the pituitary gland. It is generally presents with a clinic of sellar mass lesion with pituitary insufficiency. Histologically it is characterized by composites of histiocytes, plasma cells and giant cells with or without areas of necrosis. Tuberculosis is a very rare cause of secondary granulomatous hypophysitis. We report a case presented with hypopituitarism symptoms due to tuberc...

Objective: Radioiodine (RAI), surgical and anti-thyroid drug therapy are the main options to treat Graves’ disease (GD). The aim of this study was to investigate theurapeutic options, their efficacy and adverse reactions of prophilthiouracil (PTU) and methimazole (MMI).Design: A total of 650 patients with GD were evaluated retrospectively. Treatments, adverse reactions, clinical and laboratory results were recorded. After 18 months of primary medica...